报告题目：Controlled Selective Functionalization of Anionic Boron Cages

报告人: 浙江大学Simon Duttwyler教授

报告时间: 7月2日 下午2:30-3:30

报告地点：生化学院7幢2楼会议室

报告人简介：

Prof. Simon Duttwyler obtained his PhD degree from the University of Zurich in 2010. He was a postdoctoral researcher at Yale University from 2010-2013. Afterwards, he joined Zhejiang University as a research professor in the Department of Chemistry as a 1000 Young Talents fellow. He became a full professor in January 2019. His group focuses on the chemistry of cage-shaped boron compounds based on the scaffolds [B₁₂H₁₂]^2– and [CB₁₁H₁₂]^–. Icosahedral boron clusters are unique chemical building blocks that generally feature high stability, low toxicity and broad tunability in terms of chemical and physical properties. In particular, they study the organometallic chemistry of boron clusters and develop selective methods for their derivatization. One of the key strategies is transition metal-mediated B–H activation. Their transition metal-catalyzed transformations have provided access to a large number of tailor-made functionalized boron cages. Currently they apply these compounds in various fields such as ligand design/supramolecular chemistry, medicinal chemistry and materials science.

Selected publications

1. R. Dontha, T. Zhu, Y. Shen, M. Wörle*, X. Hong*, S. Duttwyler*，A 3D Analogue of Phenyllithium: Solution-Phase, Solid-State and Computational Study of the Lithiacarborane [Li–CB₁₁H₁₁]^–, Angew. Chem. Int. Ed. 2019, 58, 19007–19013.

2. Y. Shen, K. Zhang, X. Liang, R. Dontha, S. Duttwyler* Highly selective palladium-catalyzed one-pot, five-fold B–H/C–H cross coupling of monocarboranes with alkenes, Chem. Sci.2019, 10, 4177–4184.

3. F. Lin, J.-L. Yu, Y. Shen, S.-Q. Zhang, B. Spingler, J. Liu, X. Hong*, S. Duttwyler*, Palladium-Catalyzed Selective Five-Fold Cascade Arylation of the 12-Vertex Monocarborane Anion by B–H Activation, J. Am. ChemSoc. 2018, 140, 13798–13807.

4. Y. Zhang, Y. Sun, F. Lin, J. Liu, S. Duttwyler*, Rh(III)-Catalyzed Room Temperature Alkenylation–Annulation of closo-Dodecaborate Anions via Double B–H Activation'. Angew. Chem. Int. Ed.2016, 55, 15609–15614.

5. Y. Zhang, J. Hu, R. Krishna, L. Wang, L. Yang, X. Cui, S. Duttwyler*, H. Xing*, Rational design of microporous MOFs with anionic boron cluster functionality and cooperative dihydrogen binding sites for highly selective capture of acetylene, Angew. Chem. Int. Ed. 2020, 59, 17664–17669.

6. Y. Zhang, L. Yang, L. Wang, S. Duttwyler*, H. Xing*, A Microporous Metal-Organic Framework Supramolecularly Assembled from a Cu(II) Dodecaborate Cluster Complex for Selective Gas Separation, Angew. Chem. Int. Ed. 2019, 58, 8145–8150.